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Transfusion of the wrong blood type can cause


A) recipient antibody activating the complement cascade to attack the RBCs.
B) fever and anemia.
C) systemic shock and kidney failure.
D) massive hemolysis of the donor RBCs.
E) All of these choices are correct.

F) A) and B)
G) B) and E)

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Which of the following can cause secondary acquired immunodeficiencies in T-cells and B cells?


A) radiation
B) chemotherapy
C) organic disease
D) infection
E) All of these choices are correct.

F) B) and E)
G) All of the above

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A xenograft is a tissue exchange


A) between identical twins.
B) between siblings.
C) from one site on the body to another site.
D) between individuals of different species.

E) All of the above
F) C) and D)

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The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

A) True
B) False

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Write a definition for immunopathology and discuss the four major categories of immune system responses with specific examples for each.

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Immunopathology is the study of diseases...

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After a bone marrow transplant, the recipient's blood type may change to the blood type of the donor.

A) True
B) False

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Indicate which of the following are participants in Type 2 hypersensitivity reactions.Check all that apply.


A) IgG and IgM antibodies
B) IgE antibodies
C) complement proteins
D) Cells expressing foreign antigens or autoantigens.
E) bacterial cells
F) TC cells
G) NK cells

H) A) and B)
I) B) and G)

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All of the following are examples of autoimmune diseases, except


A) multiple sclerosis.
B) Grave's disease.
C) Hashimoto thyroiditis.
D) myasthenia gravis.
E) Wiskott-Aldrich syndrome.

F) B) and E)
G) A) and D)

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Cancer cells can not displace normal blood cells and bone marrow.

A) True
B) False

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Erythroblastosis fetalis can be prevented by


A) injecting the mother with antibodies against the Rh factor late in the pregnancy and after giving birth.
B) treating the fetus with immune globulin.
C) birth by cesarean section.
D) treating the mother with RhoGAM early in the pregnancy.

E) A) and B)
F) None of the above

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Atopy and anaphylaxis are hypersensitivities in the category


A) Type 1 only.
B) Type 1 and Type 4.
C) Type 4 only.
D) Type 1, Type 2, Type 3.
E) Type 1, Type 2, Type 3, and Type 4.

F) A) and E)
G) D) and E)

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The _____ dose of an allergen results in signs and symptoms of the allergy.

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Severe combined immunodeficiencies (SCIDs) are due to


A) autoantibodies.
B) delayed hypersensitivity.
C) congenital absence or immaturity of the thymus gland.
D) failure of B cell development and maturity.
E) a genetic defect in the development of both T-cells and B cells.

F) B) and C)
G) A) and C)

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Human blood types involve all the following, except


A) MHC genes.
B) ABO antigen markers.
C) inheritance of two of three possible alleles.
D) genetically determined glycoprotein markers.
E) genes that code for an enzyme that adds a terminal carbohydrate to RBC receptors.

F) All of the above
G) B) and C)

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Contact dermatitis involves


A) a sensitizing and provocative dose.
B) allergen entering the skin.
C) T-lymphocytes secrete inflammatory cytokines.
D) itchy papules and blisters.
E) All of these choices are correct.

F) B) and D)
G) None of the above

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Which event releases the chemical mediators?


A) degranulation
B) binding of allergen to adjacent IgE binding sites on mast cells and basophils
C) binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle.
E) Prostaglandins cause vasodilation and increased vascular permeability.

F) C) and D)
G) B) and E)

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The heart of a baboon transplanted to a human would be a/an


A) xenograft.
B) autograft.
C) allograft.
D) heterograft.
E) homograft.

F) A) and B)
G) C) and E)

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What will be the immediate action of allergen when it enters the body for a second time?


A) degranulation
B) bonding of allergen to adjacent IgE binding sites on mast cells and basophils
C) binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle.
E) Prostaglandins cause vasodilation and increased vascular permeability.

F) A) and E)
G) A) and B)

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Compare and contrast local atopies and contact dermatitis with regard to: a) components and events of the immune response, b) tissue damaging mediators, and c) two examples of each.

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a) Components and events of the immune r...

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All of the following are associated with IgE_ and mast cell-mediated allergy, except


A) drug allergy.
B) eczema.
C) anaphylaxis.
D) allergic asthma.
E) systemic lupus erythematosus.

F) A) and B)
G) A) and D)

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