Question 1

Autoimmunity is typically due to

Accepted Answer

A)  autoantibodies and T cells.
B)  a transfusion reaction.
C)  IgE and mast cells.
D)  graft rejection.
E)  a deficiency in T-cell development.F) A) and B)
G) None of the above

Question 2

Histamine causes all of the following except

Accepted Answer

A)  relaxation of vascular smooth muscle.
B)  pruritis and headache.
C)  increased sensitivity to pain.
D)  wheal and flare reaction in skin.
E)  constriction of smooth muscle of bronchi and the intestine.F) A) and B)
G) C) and D)

Question 3

Which of the following is not a possible outcome of a type I hypersensitivity reaction?

Accepted Answer

A)  Diarrhea
B)  Rashes
C)  Contact dermatitis
D)  Sneezing
E)  RhinitisF) B) and C)
G) D) and E)

Question 4

Once a mother has been sensitized to the Rh factor,

Accepted Answer

A)  all other Rh+ fetuses are at risk.
B)  she can be given RhoGAM in future pregnancies to prevent hemolytic disease of the newborn.
C)  she can never again have a low risk pregnancy.
D)  only future Rh- fetuses are at risk.
E)  None of the choices are correct.F) None of the above
G) B) and E)

Question 5

Autoantibodies cause tissue injury in all of the following diseases except

Accepted Answer

A)  multiple sclerosis.
B)  tuberculin reaction.
C)  rheumatoid arthritis.
D)  myasthenia gravis.
E)  Graves'disease.F) All of the above
G) C) and D)

Question 6

A second encounter with an allergen that causes a response is called the _____ dose.

Accepted Answer

A)  sensitizing
B)  provocative
C)  allergic
D)  hypersensitivity
E)  desensitizingF) A) and B)
G) A) and D)

Question 7

Any heightened immune response resulting in tissue damage is called a(n)  ______.

Accepted Answer

A)  immunodeficiency
B)  desensitization
C)  autoimmune disease
D)  hypersensitivity
E)  transfusion reactionF) All of the above
G) A) and B)

Question 8

Corticosteroids will

Accepted Answer

A)  inhibit the activity of lymphocytes.
B)  bind to histamine receptors on target organs.
C)  block synthesis of leukotrienes.
D)  reverse spasms of respiratory smooth muscles.E) C) and D)
F) None of the above

Question 9

Epinephrine

Accepted Answer

A)  inhibits the activity of lymphocytes.
B)  reverses constriction of airways.
C)  is an antihistamine.
D)  causes desensitization.E) None of the above
F) C) and D)

Question 10

Allergies run in families because

Accepted Answer

A)  the variable region of antibodies is genetically determined.
B)  immunoglobulins pass from mother to fetus.
C)  immunoglobulins pass through breast milk.
D)  the relative production of IgE is inherited.E) None of the above
F) A) and D)

Question 11

Which of the following pairs is mismatched?

Accepted Answer

A)  Food allergy - type I hypersensitivity
B)  Poison ivy dermatitis - type IV hypersensitivity
C)  Transfusion reaction - type II hypersensitivity
D)  Hay fever - type IV hypersensitivity
E)  Serum sickness - type III hypersensitivityF) A) and D)
G) C) and D)

Question 12

Which of the following is not a possible explanation for the origin of autoimmune diseases?
A.Sequestered antigens
B.Forbidden clones
C.Molecular mimicry
D.The gut microbiome
E.All the choices are currently being investigated as possible explanations.

Accepted Answer

A. Sequestered antigens
B. For...

Question 13

Which of the following is not true of type III hypersensitivity?

Accepted Answer

A)  The Arthus reaction is a local response.
B)  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues.
C)  It involves an immune complex reaction.
D)  Serum sickness is a systemic response.
E)  It involves production of IgE antibodies.F) C) and E)
G) A) and D)

Question 14

Which of the following is not a target for immune complex deposition?

Accepted Answer

A)  Heart and lungs
B)  Brain
C)  Kidneys
D)  Joints
E)  Blood vessels and skinF) B) and D)
G) None of the above

Question 15

SCID is defined by a lack of functional B and T cells which eliminates protection by humoral and cell-mediated immunity.Which of the following is true?

Accepted Answer

A)  A genetic defect disrupts the development of the lymphocytic cell lines.
B)  A genetic mutation renders the individual incapable of removing a toxic DNA metabolite from lymphocytes, which ultimately destroys them.
C)  Genes coding for B and T cell receptors are mutated so the cells are incapable of binding antigens.
D)  Genes that code for interleukin receptors are mutated so the individual's B and T cells do not receive the activation signals, rendering them useless.
E)  All of the above describe cases of SCID.F) A) and C)
G) A) and B)

Question 16

All of the following are associated with IgE and mast-cell-mediated allergy except ______.

Accepted Answer

A)  allergic asthma
B)  systemic lupus erythematosus
C)  drug allergies
D)  eczema
E)  anaphylaxisF) B) and E)
G) A) and B)

Question 17

Fungal spores and animal dander are considered to be which type of allergen?

Accepted Answer

A)  Injectant
B)  Contactant
C)  Inhalant
D)  IngestantE) B) and C)
F) A) and B)

Question 18

Bee sting venom is considered to be which type of allergen?

Accepted Answer

A)  Injectant
B)  Ingestant
C)  Inhalant
D)  ContactantE) A) and D)
F) A) and C)

Question 19

An effective test to determine whether an individual is allergic to a specific substance is to

Accepted Answer

A)  test for the allergen in the blood.
B)  test for levels of IgE specific for the allergen.
C)  test for high levels of IgG in the serum.
D)  inject high levels of the allergen so see if the patient goes into anaphylactic shock.E) A) and B)
F) A) and C)

Question 20

A seasonal reaction to inhaled allergens is ______.

Accepted Answer

A)  eczema
B)  asthma
C)  atopic dermatitis
D)  anaphylaxis
E)  allergic rhinitisF) None of the above
G) A) and B)

Exam 16: Disorders in Immunity

Histamine causes all of the following except

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Which of the following is not a possible outcome of a type I hypersensitivity reaction?

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Which of the following is not true of type III hypersensitivity?

Correct AnswerverifiedShow Answer

A seasonal reaction to inhaled allergens is ______.

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All of the following are associated with IgE and mast-cell-mediated allergy except ______.

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Corticosteroids will

Correct AnswerverifiedShow Answer

Bee sting venom is considered to be which type of allergen?

Correct AnswerverifiedShow Answer

Which of the following is not a possible explanation for the origin of autoimmune diseases? A.Sequestered antigens B.Forbidden clones C.Molecular mimicry D.The gut microbiome E.All the choices are currently being investigated as possible explanations.

Correct AnswerverifiedA. Sequestered antigensB. For...View AnswerShow Answer

SCID is defined by a lack of functional B and T cells which eliminates protection by humoral and cell-mediated immunity.Which of the following is true?

Correct AnswerverifiedShow Answer

An effective test to determine whether an individual is allergic to a specific substance is to

Correct AnswerverifiedShow Answer

Once a mother has been sensitized to the Rh factor,

Correct AnswerverifiedShow Answer

Which of the following is not a target for immune complex deposition?

Correct AnswerverifiedShow Answer

A second encounter with an allergen that causes a response is called the _____ dose.

Correct AnswerverifiedShow Answer

Autoimmunity is typically due to

Correct AnswerverifiedShow Answer

Which of the following pairs is mismatched?

Correct AnswerverifiedShow Answer

Autoantibodies cause tissue injury in all of the following diseases except

Correct AnswerverifiedShow Answer

Epinephrine

Correct AnswerverifiedShow Answer

Fungal spores and animal dander are considered to be which type of allergen?

Correct AnswerverifiedShow Answer

Allergies run in families because

Correct AnswerverifiedShow Answer

Any heightened immune response resulting in tissue damage is called a(n) ______.

Correct AnswerverifiedShow Answer

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A. Sequestered antigens
B. For...
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