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Refer to Figure 9.1 to answer the following questions. Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions. Refer to Figure 9.1 to answer the following questions. Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions.    -Which step shows a split of one molecule into two smaller molecules? -Which step shows a split of one molecule into two smaller molecules?

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Use the following information to answer the next questions. In the presence of oxygen, the three-carbon compound pyruvate can be catabolized in the citric acid cycle. First, however, the pyruvate 1) loses a carbon, which is given off as a molecule of CO2, 2) is oxidized to form a two-carbon compound called acetate, and 3) is bonded to coenzyme A. -During cellular respiration, acetyl CoA accumulates in which location?


A) cytosol
B) mitochondrial outer membrane
C) mitochondrial inner membrane
D) mitochondrial intermembrane space
E) mitochondrial matrix

F) B) and C)
G) A) and D)

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Figure 9.3 Figure 9.3   -Which of the following normally occurs whether or not oxygen (O₂) is present? A) glycolysis B) fermentation C) oxidation of pyruvate to acetyl CoA D) citric acid cycle E) oxidative phosphorylation (chemiosmosis) -Which of the following normally occurs whether or not oxygen (O₂) is present?


A) glycolysis
B) fermentation
C) oxidation of pyruvate to acetyl CoA
D) citric acid cycle
E) oxidative phosphorylation (chemiosmosis)

F) A) and D)
G) None of the above

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Use the following information to answer the next questions. In the presence of oxygen, the three-carbon compound pyruvate can be catabolized in the citric acid cycle. First, however, the pyruvate 1) loses a carbon, which is given off as a molecule of CO2, 2) is oxidized to form a two-carbon compound called acetate, and 3) is bonded to coenzyme A. -These three steps result in the formation of


A) acetyl CoA, O₂, and ATP.
B) acetyl CoA, FADH₂, and CO₂.
C) acetyl CoA, FAD, H₂, and CO₂.
D) acetyl CoA, NADH, H⁺, and CO₂.
E) acetyl CoA, NAD⁺, ATP, and CO₂.

F) C) and E)
G) C) and D)

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Refer to Figure 9.1 to answer the following questions. Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions. Refer to Figure 9.1 to answer the following questions. Figure 9.1 illustrates some of the steps (reactions)  of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions.    -A molecule that is phosphorylated A) has been reduced as a result of a redox reaction involving the loss of an inorganic phosphate. B) has a decreased chemical reactivity; it is less likely to provide energy for cellular work. C) has been oxidized as a result of a redox reaction involving the gain of an inorganic phosphate. D) has an increased chemical reactivity; it is primed to do cellular work. E) has less energy than before its phosphorylation and therefore less energy for cellular work. -A molecule that is phosphorylated


A) has been reduced as a result of a redox reaction involving the loss of an inorganic phosphate.
B) has a decreased chemical reactivity; it is less likely to provide energy for cellular work.
C) has been oxidized as a result of a redox reaction involving the gain of an inorganic phosphate.
D) has an increased chemical reactivity; it is primed to do cellular work.
E) has less energy than before its phosphorylation and therefore less energy for cellular work.

F) A) and E)
G) C) and E)

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Figure 9.3 Figure 9.3   -Which metabolic pathway is common to both fermentation and cellular respiration of a glucose molecule? A) the citric acid cycle B) the electron transport chain C) glycolysis D) synthesis of acetyl CoA from pyruvate E) reduction of pyruvate to lactate -Which metabolic pathway is common to both fermentation and cellular respiration of a glucose molecule?


A) the citric acid cycle
B) the electron transport chain
C) glycolysis
D) synthesis of acetyl CoA from pyruvate
E) reduction of pyruvate to lactate

F) A) and C)
G) A) and D)

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Figure 9.3 Figure 9.3   -Which of the following most accurately describes what is happening along this chain? A) Chemiosmosis is coupled with electron transfer. B) Each electron carrier alternates between being reduced and being oxidized. C) ATP is generated at each step. D) Energy of the electrons increases at each step. E) Molecules in the chain give up some of their potential energy. -Which of the following most accurately describes what is happening along this chain?


A) Chemiosmosis is coupled with electron transfer.
B) Each electron carrier alternates between being reduced and being oxidized.
C) ATP is generated at each step.
D) Energy of the electrons increases at each step.
E) Molecules in the chain give up some of their potential energy.

F) A) and D)
G) B) and E)

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Figure 9.3 Figure 9.3   -An organism is discovered that consumes a considerable amount of sugar, yet does not gain much weight when denied air. Curiously, the consumption of sugar increases as air is removed from the organism's environment, but the organism seems to thrive even in the absence of air. When returned to normal air, the organism does fine. Which of the following best describes the organism? A) It must use a molecule other than oxygen to accept electrons from the electron transport chain. B) It is a normal eukaryotic organism. C) The organism obviously lacks the citric acid cycle and electron transport chain. D) It is an anaerobic organism. E) It is a facultative anaerobe. -An organism is discovered that consumes a considerable amount of sugar, yet does not gain much weight when denied air. Curiously, the consumption of sugar increases as air is removed from the organism's environment, but the organism seems to thrive even in the absence of air. When returned to normal air, the organism does fine. Which of the following best describes the organism?


A) It must use a molecule other than oxygen to accept electrons from the electron transport chain.
B) It is a normal eukaryotic organism.
C) The organism obviously lacks the citric acid cycle and electron transport chain.
D) It is an anaerobic organism.
E) It is a facultative anaerobe.

F) None of the above
G) B) and C)

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Figure 9.3 Figure 9.3   -Glycolysis is thought to be one of the most ancient of metabolic processes. Which statement supports this idea? A) Glycolysis is the most widespread metabolic pathway. B) Glycolysis neither uses nor needs O₂. C) Glycolysis is found in all eukaryotic cells. D) The enzymes of glycolysis are found in the cytosol rather than in a membrane-enclosed organelle. E) Ancient prokaryotic cells, the most primitive of cells, made extensive use of glycolysis long before oxygen was present in Earth's atmosphere. -Glycolysis is thought to be one of the most ancient of metabolic processes. Which statement supports this idea?


A) Glycolysis is the most widespread metabolic pathway.
B) Glycolysis neither uses nor needs O₂.
C) Glycolysis is found in all eukaryotic cells.
D) The enzymes of glycolysis are found in the cytosol rather than in a membrane-enclosed organelle.
E) Ancient prokaryotic cells, the most primitive of cells, made extensive use of glycolysis long before oxygen was present in Earth's atmosphere.

F) B) and E)
G) C) and D)

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Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions. Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions.    -A young animal has never had much energy. He is brought to a veterinarian for help and is sent to the animal hospital for some tests. There they discover his mitochondria can use only fatty acids and amino acids for respiration, and his cells produce more lactate than normal. Of the following, which is the best explanation of his condition? A) His mitochondria lack the transport protein that moves pyruvate across the outer mitochondrial membrane. B) His cells cannot move NADH from glycolysis into the mitochondria. C) His cells contain something that inhibits oxygen use in his mitochondria. D) His cells lack the enzyme in glycolysis that forms pyruvate. E) His cells have a defective electron transport chain, so glucose goes to lactate instead of to acetyl CoA. -A young animal has never had much energy. He is brought to a veterinarian for help and is sent to the animal hospital for some tests. There they discover his mitochondria can use only fatty acids and amino acids for respiration, and his cells produce more lactate than normal. Of the following, which is the best explanation of his condition?


A) His mitochondria lack the transport protein that moves pyruvate across the outer mitochondrial membrane.
B) His cells cannot move NADH from glycolysis into the mitochondria.
C) His cells contain something that inhibits oxygen use in his mitochondria.
D) His cells lack the enzyme in glycolysis that forms pyruvate.
E) His cells have a defective electron transport chain, so glucose goes to lactate instead of to acetyl CoA.

F) A) and D)
G) A) and B)

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The ATP made during glycolysis is generated by


A) substrate-level phosphorylation.
B) electron transport.
C) photophosphorylation.
D) chemiosmosis.
E) oxidation of NADH to NAD⁺.

F) A) and E)
G) B) and D)

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Refer to Figure 9.1 to answer the following questions. Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions. Refer to Figure 9.1 to answer the following questions. Figure 9.1 illustrates some of the steps (reactions)  of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions.    -Why is glycolysis described as having an investment phase and a payoff phase? A) It both splits molecules and assembles molecules. B) It attaches and detaches phosphate groups. C) It uses glucose and generates pyruvate. D) It shifts molecules from cytosol to mitochondrion. E) It uses stored ATP and then forms a net increase in ATP. -Why is glycolysis described as having an investment phase and a payoff phase?


A) It both splits molecules and assembles molecules.
B) It attaches and detaches phosphate groups.
C) It uses glucose and generates pyruvate.
D) It shifts molecules from cytosol to mitochondrion.
E) It uses stored ATP and then forms a net increase in ATP.

F) A) and B)
G) A) and E)

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Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions. Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions.    -During oxidative phosphorylation, H₂O is formed. Where does the oxygen for the synthesis of the water come from? A) carbon dioxide (CO₂)  B) glucose (C₆H₁₂O₆)  C) molecular oxygen (O₂)  D) pyruvate (C₃H₃O₃⁻)  E) lactate (C₃H₅O₃⁻) -During oxidative phosphorylation, H₂O is formed. Where does the oxygen for the synthesis of the water come from?


A) carbon dioxide (CO₂)
B) glucose (C₆H₁₂O₆)
C) molecular oxygen (O₂)
D) pyruvate (C₃H₃O₃⁻)
E) lactate (C₃H₅O₃⁻)

F) A) and E)
G) B) and C)

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Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions. Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions.    -How many molecules of carbon dioxide (CO₂) would be produced by five turns of the citric acid cycle? A) 2 B) 5 C) 10 D) 12 E) 60 -How many molecules of carbon dioxide (CO₂) would be produced by five turns of the citric acid cycle?


A) 2
B) 5
C) 10
D) 12
E) 60

F) B) and C)
G) A) and C)

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C

Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions. Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions.    -Cellular respiration harvests the most chemical energy from which of the following? A) substrate-level phosphorylation B) chemiosmotic phosphorylation C) converting oxygen to ATP D) transferring electrons from organic molecules to pyruvate E) generating carbon dioxide and oxygen in the electron transport chain -Cellular respiration harvests the most chemical energy from which of the following?


A) substrate-level phosphorylation
B) chemiosmotic phosphorylation
C) converting oxygen to ATP
D) transferring electrons from organic molecules to pyruvate
E) generating carbon dioxide and oxygen in the electron transport chain

F) A) and B)
G) A) and E)

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Figure 9.3 Figure 9.3   -When muscle cells undergo anaerobic respiration, they become fatigued and painful. This is now known to be caused by A) buildup of pyruvate. B) buildup of lactate. C) increase in sodium ions. D) increase in potassium ions. E) increase in ethanol. -When muscle cells undergo anaerobic respiration, they become fatigued and painful. This is now known to be caused by


A) buildup of pyruvate.
B) buildup of lactate.
C) increase in sodium ions.
D) increase in potassium ions.
E) increase in ethanol.

F) B) and E)
G) A) and B)

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Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions. Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions.    -The primary role of oxygen in cellular respiration is to A) yield energy in the form of ATP as it is passed down the respiratory chain. B) act as an acceptor for electrons and hydrogen, forming water. C) combine with carbon, forming CO₂. D) combine with lactate, forming pyruvate. E) catalyze the reactions of glycolysis. -The primary role of oxygen in cellular respiration is to


A) yield energy in the form of ATP as it is passed down the respiratory chain.
B) act as an acceptor for electrons and hydrogen, forming water.
C) combine with carbon, forming CO₂.
D) combine with lactate, forming pyruvate.
E) catalyze the reactions of glycolysis.

F) A) and C)
G) B) and D)

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Which process in eukaryotic cells will proceed normally whether oxygen (O₂) is present or absent?


A) electron transport
B) glycolysis
C) the citric acid cycle
D) oxidative phosphorylation
E) chemiosmosis

F) C) and E)
G) B) and D)

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Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions. Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions.    -Energy released by the electron transport chain is used to pump H+ ions into which location? A) cytosol B) mitochondrial outer membrane C) mitochondrial inner membrane D) mitochondrial intermembrane space E) mitochondrial matrix -Energy released by the electron transport chain is used to pump H+ ions into which location?


A) cytosol
B) mitochondrial outer membrane
C) mitochondrial inner membrane
D) mitochondrial intermembrane space
E) mitochondrial matrix

F) C) and D)
G) A) and D)

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D

Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions. Refer to Figure 9.2, showing the citric acid cycle, as a guide to answer the following questions.    -In liver cells, the inner mitochondrial membranes are about 5 X the area of the outer mitochondrial membranes, and about 17 X that of the cell's plasma membrane. What purpose must this serve? A) It allows for increased rate of glycolysis. B) It allows for increased rate of the citric acid cycle. C) It increases the surface for oxidative phosphoryation. D) It increases the surface for substrate-level phosphorylation. E) It allows the liver cell to have fewer mitochondria. -In liver cells, the inner mitochondrial membranes are about 5 X the area of the outer mitochondrial membranes, and about 17 X that of the cell's plasma membrane. What purpose must this serve?


A) It allows for increased rate of glycolysis.
B) It allows for increased rate of the citric acid cycle.
C) It increases the surface for oxidative phosphoryation.
D) It increases the surface for substrate-level phosphorylation.
E) It allows the liver cell to have fewer mitochondria.

F) A) and B)
G) B) and E)

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C

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